Article

Three-Dimensional (3D) systems provide a more realistic tool to model Parkinson’s Disease (PD) in vitro

2024-09-17

Abstract excerpt

Parkinson’s Disease (PD), which exhibits a rapidly developing pathology, is one of the most devastating neurodegenerative diseases. To understand its molecular and cellular mechanisms and to attain a truly effective treatment, it is essential to develop standard, rapid, and reliable in vitro testing platforms for diseases. Classical two-dimensional (2D) cell culture is the starting point for the study of PD diagno...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8634e00f-4ff8-5391-bd63-9edca468a039
DOI: 10.22541/au.172656825.52648585/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Three-Dimensional (3D) systems provide a more realistic tool to model Parkinson’s Disease (PD) in vitroDOI 10.22541/au.172656825.52648585/v1Read

3D biocomposite culture enhances differentiation of dopamine-like neurons from SH-SY5Y cells: A model for studying Parkinson's disease phenotypes.Semantic proximity Read

Modeling Cell-Cell Interactions in Parkinson’s Disease Using Human Stem Cell-Based ModelsSemantic proximity Read

Brain Organoids in Parkinson’s Disease Drug Development: Human-Specific Models for Translational DiscoverySemantic proximity Read

The multifaceted role of LRRK2 in Parkinson's disease: From human iPSC to organoids.Semantic proximity Read

Robust In Vitro Models for Studying Parkinson’s Disease? LUHMES Cells and SH-SH5Y CellsSemantic proximity Read

Comprehensive Perspectives on Experimental Models for Parkinson’s DiseaseSemantic proximity Read

Organoid and pluripotent stem cells in Parkinson’s disease modeling: an expert view on their value to drug discoverySemantic proximity Read

Differences between Cerebral Organoids Derived from a non-PD and a Parkinson’s Patient: A Potential Vulnerability for Neuroinvasive VirusesSemantic proximity Read

Released mitochondrial DNA and neurofilament light chain as Parkinson’s disease phenotypes in patient-specific midbrain assembloidsSemantic proximity Read

Parkinson's Disease and Mesenchymal Stem Cells: Potential for Cell-Based TherapySemantic proximity Read

Development of a multi-sensor integrated midbrain organoid-on-a-chip platform for studying Parkinson’s diseaseSemantic proximity Read

Classic and evolving animal models in Parkinson's disease.Semantic proximity Read