Article

Regulation of supply and demand for maternal nutrients in mammals by imprinted genes

2003-01-24

Abstract excerpt

The placenta has evolved in eutherian mammals primarily to provide nutrients for the developing fetus. The genetic control of the regulation of supply and demand for maternal nutrients is not understood. In this review we argue that imprinted genes have central roles in controlling both the fetal demand for, and the placental supply of, maternal nutrients. Recent studies on Igf2 (insulin-like growth factor 2) knoc...

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Literature Corpus work: 86034b64-2336-5232-bcab-b1738c54d5f9
DOI: 10.1113/jphysiol.2002.033274

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