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Integration of MRI radiomics and germline genetics to predict the IDH mutation status of gliomas

2024-07-17

Abstract excerpt

<h4>ABSTRACT</h4> The molecular profiling of gliomas for isocitrate dehydrogenase ( IDH ) mutations currently relies on resected tumor samples, highlighting the need for non-invasive, preoperative biomarkers. We investigated the integration of glioma polygenic risk scores (PRS) and radiographic features for prediction of IDH mutation status. We used 256 radiomic features, a glioma PRS and demographic information i...

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Literature Corpus work
8601cc1c-b82b-5433-b555-658db17aacc9
DOI
10.1101/2024.07.16.24310519
Open publication

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Integration of MRI radiomics and germline genetics to predict the IDH mutation status of gliomasDOI 10.1101/2024.07.16.24310519
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