Article

Not All Saliva Samples Are Equal: The Role of Cellular Heterogeneity in DNA methylation and Epigenetic Age Analyses with Biological and Psychosocial Factors

2024-11-11

Abstract excerpt

Saliva is widely used in biomedical population research, including epigenetic analyses to investigate gene-environment interplay and identify biomarkers. Its minimally invasive collection procedure makes it ideal for studies in pediatric populations. Saliva is a heterogenous tissue composed of immune and buccal epithelial cells (BEC). Amongst the many epigenetic marks, DNA methylation (DNAm) is the most studied in...

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Literature Corpus work: 85f6d90f-ef1b-59a2-9d60-1bef078ddf0c
DOI: 10.1101/2024.11.08.621377

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