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Combining a novel ensemble model and multiplex methylation SNaPshot assays for saliva age prediction and cross-platform data analysis

30 May 2025

Abstract excerpt

BACKGROUND: DNA methylation is a pivotal biomarker for age prediction. However, most studies focus on blood-derived data, with limited research on saliva, and the inability to directly analyze methylation data across diverse platforms constrains predictive accuracy. RESULTS: We identified 10 age-related CpG sites in saliva (cg00481951, cg07547549, cg10501210, cg13654588, cg14361627, cg15480367, cg17110586,...

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PMID: 40448028
DOI: 10.1186/s12864-025-11713-8

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