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Article

Saliva as a potential diagnostic medium: DNA methylation biomarkers for disorders beyond the oral cavity

20 Jun 2025

Abstract excerpt

Saliva is an accessible biofluid with potential for non-invasive disease diagnostics. This study explores how genetic susceptibility to common diseases is reflected in DNA methylation (DNAm) and gene expression profiles in saliva. We constructed cis-mQTL (n = 345) and cis-eQTL (n = 277) datasets and examined correlations between DNAm and gene expression. Saliva QTLs were integrated with summary statistics from 36...

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Share to Epigenetics and DNA Methylation
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PMID: 40541940
DOI: 10.1038/s41525-025-00509-0

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