Article

A novel approach to modeling transcriptional heterogeneity identifies the oncogene candidate <i>CBX2</i> in invasive breast carcinoma

2018-04-20

Abstract excerpt

Oncogenes promote the development of and serve as therapeutic targets against subsets of cancers. Here, a new statistical approach that captures transcriptional heterogeneity in tumor and adjacent normal (i.e. tumor-free) mRNA expression profiles was developed to identify oncogene candidates that were overexpressed in a subset of breast tumors. Intronic DNA methylation was strongly associated with the overexpressi...

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Literature Corpus work: 85c6d658-cf07-5bf5-9270-e6e4c233a5d0
DOI: 10.1101/303396

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