RapTCR: Rapid exploration and visualization of T-cell receptor repertoires

Abstract excerpt

<h4> A bstract </h4> <h4>Motivation</h4> The acquisition of T-cell receptor (TCR) repertoire sequence data has become faster and cheaper due to advancements in high-throughput sequencing. However, fully exploiting the diagnostic and clinical potential within these TCR repertoires requires a thorough understanding of the inherent repertoire structure. Hence, visualizing the full space of TCR sequences could be...

Topics

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• Genetic Variation
• High-Throughput Nucleotide Sequencing
• Immunogenetics
• Immunoglobulins
• Receptors, Antigen, T-Cell
• Software
• T-cell and B-cell Immunology
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

85b020a0-6bdd-5239-9fb4-1df24f33c8b8

DOI

10.1101/2023.09.13.557604