Article

Neuron-derived exosomes trigger a PD-L1-mediated broad suppression of T cells in Parkinson’s disease

2022-10-05

Abstract excerpt

<title>Abstract</title> <p>Background Adaptive immunity plays an important role in Parkinson’s disease (PD). Multiple lines of evidence indicate a significant decrease in peripheral T cells in PD patients. Although this suppression impacts both overall immune and neuroimmune response in Parkinson’s disease, there is currently no mechanistic explanation for this important phenomenon reported by many clinical stud...

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Literature Corpus work: 85838a86-3876-5b4e-91c8-1b46a61fcc19
DOI: 10.21203/rs.3.rs-2109216/v1

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