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Exosomes in Parkinson disease

29 Dec 2020

Abstract excerpt

Parkinson disease (PD) is a prevalent neurodegenerative disease, in which the formation of misfolded and aggregated α-synuclein is a key neuropathological hallmark. Recent studies reveal that extracellular vesicles such as exosomes present a potential mechanism for propagation of pathological α-synuclein throughout the brain. The ability of exosomes to transport proteins and genetic material between cells,...

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PMID: 33372290
DOI: 10.1111/jnc.15288

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