Article

“Informative Use of Cycle-Threshold Values to Account for Sampling Variability in Pathogen Detection”

2023-03-27

Abstract excerpt

Nucleic acid amplification tests, like real-time polymerase chain reaction, are widely used for pathogen detection; however, their interpretation rarely accounts for sampling variability. Instead, cycle threshold values are often categorized reducing precision. We describe how pathogen cycle threshold values can be normalized to endogenous host gene expression to correct for sampling variability and compare the va...

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Identifiers and source

Literature Corpus work: 8556f90d-7e50-532c-ae9c-8b09872fe16a
DOI: 10.1101/2023.03.21.23287544

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