Article

Diagnostic host gene signature to accurately distinguish enteric fever from other febrile diseases

2018-05-21

Abstract excerpt

<h4>ABSTRACT</h4> Misdiagnosis of enteric fever is a major global health problem resulting in patient mismanagement, antimicrobial misuse and inaccurate disease burden estimates. Applying a machine-learning algorithm to host gene expression profiles, we identified a diagnostic signature which could accurately distinguish culture-confirmed enteric fever cases from other febrile illnesses (AUROC<95%). Applying this...

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Literature Corpus work: 14e3495c-60c6-5332-870c-25989d6e1209
DOI: 10.1101/327429

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