Article

The GD3 ganglioside promotes cell growth, plasticity and chemotherapy resistance of human glioblastoma cancer stem cells

2025-03-31

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Glioblastoma is the most aggressive primary brain tumour with no curative treatment and inevitable relapse. Therapeutic resistance is, at least, related to the presence of cancer stem-like cells in these tumours. Here, we aimed to demonstrate that the GD3 ganglioside was a relevant marker and actionable target for glioblastoma cancer stem-like cells.<bold>Methods...

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Literature Corpus work: 854fc2ae-4e1b-5a04-99d5-b5a2a9ba4cee
DOI: 10.21203/rs.3.rs-5246487/v1

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