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Targeted rescue of synaptic plasticity improves cognitive decline after severe systemic inflammation

2021-03-06

Abstract excerpt

Sepsis-associated encephalopathy (SAE) is a frequent complication in patients with severe systemic infection resulting in acute brain dysfunction and incapacitating long-term sequelae. SAE includes delirium, premature death, post-traumatic stress disorder, and major long-term cognitive impairment. The underlying pathophysiology of SAE is largely unresolved and specific treatment options are missing. We induced the...

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Identifiers and source

Literature Corpus work
8548da27-9124-5108-8c05-28314b0f44aa
DOI
10.1101/2021.03.04.433352
Open publication

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Targeted rescue of synaptic plasticity improves cognitive decline after severe systemic inflammationDOI 10.1101/2021.03.04.433352
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