Article

Proteomic profiling of aortic wall remodeling in pediatric coarctation of the aorta: an integrative DIA proteomics and histopathology study

2026-08-06

Abstract excerpt

<title>Abstract</title> <p>Background Coarctation of the aorta (CoA) is a congenital narrowing of the aorta associated with persistent vascular morbidity even after anatomical repair. The molecular features of the stenotic aortic wall remain incompletely characterized. This study aimed to define protein abundance changes in pediatric CoA tissue and integrate proteomic findings with histopathological remodeling....

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Literature Corpus work: 8544a102-7342-5e6c-8ad4-d573b5cbcbe0
DOI: 10.21203/rs.3.rs-10467332/v1

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