Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

α-Cyperone Attenuates H2O2-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2

8 Apr 2020

Abstract excerpt

α-cyperone, extracted from Cyperus rotundus, has been reported to inhibit microglia-mediated neuroinflammation. Oxidative stress and apoptosis play crucial roles in the course of Parkinson's disease (PD). PD is a common neurodegenerative disease characterized by selective death of dopaminergic neurons. This study was designed to investigate the neuroprotective effects of α-cyperone against hydrogen peroxide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Glycation End Products research
Share to Biochemical effects in animals
Share to Genomics, phytochemicals, and oxidative stress

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32322198
DOI: 10.3389/fphar.2020.00281

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

α-Cyperone Attenuates H2O2-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2PMID 32322198Read ↗

Ellagic acid protects from rotenone-induced dopaminergic neuronal damage via activation of Nrf2 signaling in astrogliaSemantic proximity Read ↗

Assessing Neuroprotective Effects of Mitoquinone on H2O2-Induced Neurotoxicity in SH-SY5Y Neuroblastoma CellsSemantic proximity Read ↗

An Interactive Review on the Role of Tocotrienols in the Neurodegenerative DisordersSemantic proximity Read ↗

Monoterpenoid Epoxidiol Ameliorates the Pathological Phenotypes of the Rotenone-Induced Parkinson's Disease Model by Alleviating Mitochondrial Dysfunction.Semantic proximity Read ↗

Scopoletin Augments DJ1/Nrf2 Signalling and Prevents Protein Aggregation in Parkinson’s diseaseSemantic proximity Read ↗

Harnessing the Therapeutic Potential of the Nrf2/Bach1 Signaling Pathway in Parkinson’s DiseaseSemantic proximity Read ↗

Targeting Nrf2-Mediated Gene Transcription by Extremely Potent Synthetic Triterpenoids Attenuate Dopaminergic Neurotoxicity in the MPTP Mouse Model of Parkinson's DiseaseSemantic proximity Read ↗

Combined neuroprotective potential of Levodopa and Resveratrol to ameliorates cognitive impairments in rotenone-induced Parkinson's disease via targeting TLR mediated neuroinflammationSemantic proximity Read ↗

Activation of Nrf2 Neuroprotective Pathways for Treatment of Parkinson’s Disease: A State of Art ReviewSemantic proximity Read ↗

Camptothecin regulates microglia polarization and exerts neuroprotective effects via the AKT/Nrf2/HO-1-NF-κB signal axis in vivo and in vitroSemantic proximity Read ↗

Camptothecin regulates microglia polarization and exerts neuroprotective effects via the AKT/Nrf2/HO-1-NF-κB signal axis in vivo and in vitroSemantic proximity Read ↗

Protective Effect of Arzanol against H2O2-Induced Oxidative Stress Damage in Differentiated and Undifferentiated SH-SY5Y CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.