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Acetylcholinesterase (AchE) receptor-based In-Silico drug discovery for Alzheimer’s Disease

2022-12-13

Abstract excerpt

In Alzheimer’s disease acetylcholine esterase is a lead enzyme for increasing the patient health. The current most effective drug was donepezil in this paper the donepezil core which is not participating in receptor-ligand binding was substituted with another core and the library was prepared. Computer-aided drug design (CADD), especially in the field of structure-based plays a significant role in the design and o...

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Literature Corpus work
84d574b8-7b0e-51bd-a179-01bc0cc42089
DOI
10.21203/rs.3.rs-2249735/v1
Open publication

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Acetylcholinesterase (AchE) receptor-based In-Silico drug discovery for Alzheimer’s DiseaseDOI 10.21203/rs.3.rs-2249735/v1
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