Article

Not a cluster of grapes, but bananas: Cord-like three-dimensional structure of cysts in ADPKD supports tubular obstruction hypothesis

2024-06-11

Abstract excerpt

<title>Abstract</title> <p>We investigated the three-dimensional structure of the kidneys of mouse models of autosomal dominant polycystic kidney disease (ADPKD), a progressive genetic kidney disease and one of the leading causes of end-stage renal disease. We performed histological observations and transparentized the kidneys for three-dimensional imaging on rapid-onset and chronic-onset models. We found that th...

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Literature Corpus work: 84b95923-da9c-5f65-a5bc-6ede0a5902cf
DOI: 10.21203/rs.3.rs-3730797/v1

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