Article

In-depth 3D Exploration of Autosomal Dominant Polycystic Kidney Disease Through Light Sheet Fluorescence Microscopy

2025-03-19

Abstract excerpt

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most prevalent genetic kidney disorder. Animal preclinical studies are one of the main tools to study this disease, often through either 2D histology imaging for high-resolution analysis or CT or MRI for full kidney segmentation. As an alternative to these modalities, we propose the use of Light Sheet Fluorescence Microscopy (LSFM) for high-resolution 3D...

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Literature Corpus work: 3ad6f943-4b04-5968-b65c-353ada104ee1
DOI: 10.1101/2025.03.18.644002

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