Article

Spatiotemporal single cell transcriptomic analysis of human gut macrophages reveals multiple functional and niche-specific subsets

2021-05-11

Abstract excerpt

Macrophages are a heterogeneous population of cells involved in tissue homeostasis, inflammation and cancer. Although macrophages are densely distributed throughout the human intestine, our understanding of how gut macrophages maintain tissue homeostasis is limited. Here we show that colonic lamina propria (LpM) and muscularis macrophages (MM) consist of monocyte-like cells that differentiate into multiple transcr...

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Literature Corpus work: 84ae0da3-7aaa-5d84-96ce-600e6d2632c7
DOI: 10.1101/2021.05.11.443586

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