Article

Longitudinal immunophenotyping to track motor progression in Parkinson’s Associated with a TH mutation

2024-01-04

Abstract excerpt

<h4>Background: </h4> and Objectives: PD is the second most common neurodegenerative disorder and the fastest growing. Genetic factors account for ∼15% of cases. Despite some consistency in symptoms across idiopathic and genetic PD cases, tracking progression and treatment response remains an important challenge especially in the development of new therapies. There have been many traditional approaches to tracking...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 848d73c4-96b9-5bda-9f64-55779fb01147
DOI: 10.1101/2024.01.03.23300647

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Longitudinal immunophenotyping to track motor progression in Parkinson’s Associated with a TH mutationDOI 10.1101/2024.01.03.23300647Read

Immunophenotyping Tracks Motor Progression in Parkinson's Disease Associated with a TH Mutation.Semantic proximity Read

Single-cell RNA sequencing of peripheral blood cells identifies transcriptomic signatures in Parkinson’s diseaseSemantic proximity Read

Immunological shifts during early-stage Parkinson’s disease identified with DNA methylation data on longitudinally collected blood samplesSemantic proximity Read

Peripheral Immune pattern in a genetic cohort of p.A53T alpha-synuclein Parkinson’s diseaseSemantic proximity Read

Abnormal B-Cell and Tfh-Cell Profiles in Patients With Parkinson DiseaseSemantic proximity Read

Parkinson’s disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patientsSemantic proximity Read

Stage-dependent phosphoproteome remodeling of Parkinson's disease blood cellsSemantic proximity Read

Exploring neuro-immune interactions in neurodegeneration : the role of B lymphocytes in Parkinson's diseaseSemantic proximity Read

Ex vivo activation unmasks a sex-convergent, exhaustion-associated CD8+ T cell expansion in Parkinson’s diseaseSemantic proximity Read

CD4+ regulatory and effector/memory T cell subsets profile motor dysfunction in Parkinson's disease.Semantic proximity Read

Quantification of huntingtin protein species in Huntington's disease patient leukocytes using optimised electrochemiluminescence immunoassays.Semantic proximity Read

Blood-brain barrier model architecture shapes peripheral immune cell trafficking in Parkinson’s diseaseSemantic proximity Read