Article

Ex vivo activation unmasks a sex-convergent, exhaustion-associated CD8+ T cell expansion in Parkinson’s disease

2026-08-18

Abstract excerpt

Parkinson’s disease (PD) affects an estimated 6.4 million men and 5.3 million women worldwide, and still lacks a validated peripheral biomarker. Brain tissue is inaccessible in living patients, making peripheral blood an attractive alternative, but existing studies have profiled immune cells almost exclusively as static, resting-state snapshots that cannot reveal how those cells function under challenge. A longitu...

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Literature Corpus work: 5b821262-6b12-50b3-ac45-cca5b553cd12
DOI: 10.64898/2026.08.13.744357

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