Article

Unravelling the Tumourigenesis Mechanisms of Oncocytic Cell Tumours: Discoveries from a Comparative Omics Study

2024-11-27

Abstract excerpt

<title>Abstract</title> <p>Oncocytic cell tumours (OCTs), formerly known as Hürthle cell tumours in thyroid, are a subset of thyroid and other endocrine neoplasms that present diagnostic and therapeutic challenges due to their variable clinical behaviour. Considering the limited exploration of transcriptomic and proteomic profiles of OCTs compared to MRNs in the literature, we conducted RNA and protein sequencing...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 843fd8c8-f28a-58dc-a4fa-a61aeac1df11
DOI: 10.21203/rs.3.rs-5337626/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Unravelling the Tumourigenesis Mechanisms of Oncocytic Cell Tumours: Discoveries from a Comparative Omics StudyDOI 10.21203/rs.3.rs-5337626/v1Read

Genomic and transcriptomic characterization of the mitochondrial-rich oncocytic phenotype on a thyroid carcinoma background.Semantic proximity Read

Multi-omics Signatures and Translational Potential to Improve Thyroid Cancer Patient OutcomeSemantic proximity Read

Genomics and Multi-Omics to Guide Clinical Management in Thyroid CancerSemantic proximity Read

Molecular Markers in Follicular and Oncocytic Thyroid Carcinomas: Clinical Application of Molecular Genetic TestingSemantic proximity Read

Multi-omics profiling of papillary thyroid microcarcinoma reveals different somatic mutations and a unique transcriptomic signature.Semantic proximity Read

Recent Improvements in Genomic and Transcriptomic Understanding of Anaplastic and Poorly Differentiated Thyroid Cancers.Semantic proximity Read

Genomic Characterization of Oncocytic Carcinoma of the Thyroid Using a Large Multi-Institutional Database.Semantic proximity Read

Integrated metabolic and genetic analysis reveals distinct features of primary differentiated thyroid cancer and its metastatic potential in humansSemantic proximity Read

A clinically applicable molecular classification of oncocytic cell thyroid nodulesSemantic proximity Read

Oncocytic Cell Carcinoma of the Thyroid with TERT Promoter Mutation Presenting as Asphyxia in an Elderly: A Case ReportSemantic proximity Read

ENDOCRINE TUMOURS: Advances in the molecular pathogenesis of thyroid cancer: lessons from the cancer genome.Semantic proximity Read

Single-cell transcriptome and genome analyses of pituitary neuroendocrine tumorsSemantic proximity Read