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Article

Genomic Characterization of Oncocytic Carcinoma of the Thyroid Using a Large Multi-Institutional Database.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 Mar 2026

Hsia Beau, Dongre Roshan, Veluvolu Vinay D, Kuzniar Julia, Bitar Gabriel, Alshaka Saif A, Bastien Amanda J, Patel Vijay A, Khaku Aliasgher

Abstract excerpt

OBJECTIVE: Characterize the somatic mutations in Oncocytic Carcinoma of the Thyroid (OCA) using a large, multi-institutional database to identify potential therapeutic targets and gain insights into tumor biology. STUDY DESIGN: Cross-sectional study. SETTING: Retrospective nationwide database review. METHODS: Genomic data from 130 OCA samples, representing 124 adult patients, were retrieved from the American...

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Identifiers

PMID: 41582704
DOI: 10.1002/ohn.70115

Genes

DAXX
TERT
MEN1
MST1R
PRKDC
TSC2
CDKN1A
KMT2D
NF1
PC
PCLO
PTEN
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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