Article

Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and SARS-CoV-2 variants

2021-12-15

Abstract excerpt

The COVID-19 pandemic has demonstrated a clear need for high-throughput, multiplexed, and sensitive assays for detecting SARS-CoV-2 and other respiratory viruses as well as their emerging variants. Here, we present microfluidic CARMEN (mCARMEN), a cost-effective virus and variant detection platform that combines CRISPR-based diagnostics and microfluidics with a streamlined workflow for clinical use. We developed t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: da1eb235-eddb-58bb-a147-8505453946b1
DOI: 10.1101/2021.12.14.21267689

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and SARS-CoV-2 variantsDOI 10.1101/2021.12.14.21267689Read

Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variantsSemantic proximity Read

Sensitive and Rapid Diagnosis of Respiratory Virus Coinfection Using a Microfluidic Chip‐Powered CRISPR/Cas12a SystemSemantic proximity Read

High-Throughput and Integrated CRISPR/Cas12a-Based Molecular Diagnosis Using a Deep Learning Enabled Microfluidic System.Semantic proximity Read

Rapid, point-of-care molecular diagnostics with Cas13Semantic proximity Read

A multiplexed Cas13-based assay with point-of-care attributes for simultaneous COVID-19 diagnosis and variant surveillanceSemantic proximity Read

A Multiplexed Cas13-Based Assay with Point-of-Care Attributes for Simultaneous COVID-19 Diagnosis and Variant SurveillanceSemantic proximity Read

Detection and identification of SARS-CoV-2 and influenza a based on microfluidic technologySemantic proximity Read

Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variantsSemantic proximity Read

Advances in Nucleic Acid Assays for Infectious Disease: The Role of Microfluidic TechnologySemantic proximity Read

OmiCrisp: A CRISPR SARS-CoV-2 test with Omicron detectionSemantic proximity Read

Accelerated RNA detection using tandem CRISPR nucleasesSemantic proximity Read

A Sample-to-Answer COVID-19 Diagnostic Device Based on Immiscible Filtration and CRISPR-Cas12a-Assisted DetectionSemantic proximity Read