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Comparative In Vivo Imaging of Retinal Structures in Tree Shrews, Humans, and Mice

1 Mar 2024

Abstract excerpt

Rodent models, such as mice and rats, are commonly used to examine retinal ganglion cell damage in eye diseases. However, as nocturnal animals, rodent retinal structures differ from primates, imposing significant limitations in studying retinal pathology. Tree shrews (Tupaia belangeri) are small, diurnal paraprimates that exhibit superior visual acuity and color vision compared with mice. Like humans, tree shrews...

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PMID: 38538082
DOI: 10.1523/eneuro.0373-23.2024

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