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Article

Optical coherence tomography for live phenotypic analysis of embryonic ocular structures in mouse models.

Journal of biomedical optics - 1 Aug 2012

Larina Irina V, Syed Saba H, Sudheendran Narendran, Overbeek Paul A, Dickinson Mary E, Larin Kirill V

Abstract excerpt

Mouse models of ocular diseases provide a powerful resource for exploration of molecular regulation of eye development and pre-clinical studies. Availability of a live high-resolution imaging method for mouse embryonic eyes would significantly enhance longitudinal analyses and high-throughput morphological screening. We demonstrate that optical coherence tomography (OCT) can be used for live embryonic ocular...

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Identifiers

PMID: 23224171
DOI: 10.1117/1.JBO.17.8.081410
PMCID: PMC3397804

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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