Article

Hydroxyurea: An Old Drug in Need of New Clinical Trials in Myeloproliferative Neoplasms

2024-08-05

Abstract excerpt

Hydroxyurea (Hu) has been a front-line therapeutic agent for myeloproliferative neoplasms (MPN) for many years and still enjoys the endorsement of experts in the field. However, several publications have reported sub-optimal response, the need for treatment interruption because of cytopenias and lack of sustained response. In all these studies, Hu was used as continuous therapy at a daily dose ranging from 500mg t...

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Literature Corpus work: 83d04c63-8576-5e97-8f9a-2126050dd17e
DOI: 10.20944/preprints202408.0323.v1

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