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Article

New data intensifies interest in hydroxyurea.

GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies - 1 Sept 1995

Santiago L G

Abstract excerpt

Newly publicized trial data are showing that hydroxyurea has strong anti-HIV activity, especially when combined with ddI, which has led to the opening of new trials testing the hydroxyurea/ddI combination. Hydroxyurea's purported mechanism of action against HIV is to inhibit a cellular enzyme, ribonucleotide reductase, that is essential for creating the special nucleotide units needed to form DNA. With fewer...

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PMID: 11362902

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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