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Autophagy shapes the peptide repertoire of rheumatoid arthritis-associated HLA class II alleles

2026-03-26

Abstract excerpt

Alternative pathways of antigen presentation are crucial in different immunological contexts such as autoimmunity and anti-microbial defense. Among these pathways, autophagy has a central role in delivering cytosolic substrates to the MHC class II compartment. However, its contribution to endogenous MHC class II presentation was only demonstrated for a few antigens. Here we focused our study on the contribution of...

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Literature Corpus work
83ce3825-921f-5114-85fe-be2111ea16c5
DOI
10.64898/2026.03.24.713950
Open publication

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Autophagy shapes the peptide repertoire of rheumatoid arthritis-associated HLA class II allelesDOI 10.64898/2026.03.24.713950
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