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Article

Autophagy‐dependent regulation of MHC‐I molecule presentation

1 May 2023

Abstract excerpt

The major histocompatibility complex (MHC) class I molecules present peptide antigens to MHC class I-restricted CD8+ T lymphocytes to elicit an effective immune response. The conventional antigen-processing pathway for MHC-I presentation depends on proteasome-mediated peptide generation and peptide loading in the endoplasmic reticulum by members of the peptide loading complex. Recent discoveries in this field...

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PMID: 37126231
DOI: 10.1002/jcb.30416

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