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Autophagy and Autophagy-Related Proteins in CNS Autoimmunity

27 Feb 2017

Abstract excerpt

Autophagy comprises a heterogeneous group of cellular pathways that enables eukaryotic cells to deliver cytoplasmic constituents for lysosomal degradation, to recycle nutrients and to survive during starvation. In addition to these primordial functions, autophagy has emerged as a key mechanism in orchestrating innate and adaptive immune responses and to shape CD4+ T cell immunity through delivery of peptides to...

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PMID: 28289410
DOI: 10.3389/fimmu.2017.00165

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