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The Therapeutic and Pathogenic Role of Autophagy in Autoimmune Diseases

31 Jul 2018

Abstract excerpt

Autophagy is a complicated cellular mechanism that maintains cellular and tissue homeostasis and integrity via degradation of senescent, defective subcellular organelles, infectious agents, and misfolded proteins. Accumulating evidence has shown that autophagy is involved in numerous immune processes, such as removal of intracellular bacteria, cytokine production, autoantigen presentation, and survival of...

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PMID: 30108582
DOI: 10.3389/fimmu.2018.01512

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