Article

<i>In silico</i> experiments uncover a novel mechanism underlying mutation rate evolution in sexually reproducing populations

2021-09-26

Abstract excerpt

Natural selection is believed to universally work to lower mutation rates (MR) due to the negative impact of mutations on individual fitness. Mutator alleles can be co-selected by genetic linkage with adaptive alleles in asexual organisms. However, sexual reproduction disrupts genetic linkage, allowing selection to efficiently eradicate mutator alleles, lowering MR to the extent limited by the overall selection ef...

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Literature Corpus work: 83ca1eec-50d2-51c0-971a-2ea892ff984a
DOI: 10.1101/2021.09.25.461822

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