Article

Transcriptional reprogramming in immune cells of HTLV-1 asymptomatic carriers and HAM/TSP patients following antiretroviral therapy

2025-10-31

Abstract excerpt

<title>Abstract</title> <p>Human T-cell lymphotropic virus type 1 (HTLV-1) causes HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chronic, immune-mediated spinal cord disease in which peripheral immune activation is thought to fuel central neuroinflammation. To delineate cell type-specific programs linked to disease, we performed single-cell RNA sequencing on the peripheral blood mononuclea...

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Literature Corpus work: 83b92b81-da49-56c3-a482-1996dfe118fc
DOI: 10.21203/rs.3.rs-7724833/v1

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