Article
Biphasic effects of IL-27 during <i>Staphylococcus aureus</i> implant-associated osteomyelitis in mice
2021-05-20
Abstract excerpt
Interleukin-27 is a pleiotropic cytokine whose reported functions during bacterial infections are debated as an area of active research. To address this, we investigated the role of IL-27 signaling during Staphylococcus aureus osteomyelitis. Clinically, we observed elevated serum IL-27 levels (20-fold higher, p<0.05) in patients with S. aureus osteomyelitis compared to uninfected patients undergoing elective tot...
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Identifiers and source
- Literature Corpus work
- 839e9e8c-4a7f-5d3a-baf4-dc80bdeb80b9
- DOI
- 10.1101/2021.05.20.444931