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Interleukin-27 in T Cell Immunity

27 Jan 2015

Abstract excerpt

Interleukin (IL)-27, a member of IL-12/IL-23 heterodimeric family of cytokines, has pleiotropic properties that can enhance or limit immune responses. IL-27 acts on various cell types, including T cells, B cells, macrophages, dendritic cells, natural killer (NK) cells and non-hematopoietic cells. Intensive studies have been conducted especially on T cells, revealing that various subsets of T cells respond...

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PMID: 25633106
DOI: 10.3390/ijms16022851

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