Article

Haplotype sharing provides insights into fine-scale population history and disease in Finland

2017-10-13

Abstract excerpt

Finland provides unique opportunities to investigate population and medical genomics because of its adoption of unified national electronic health records, detailed historical and birth records, and serial population bottlenecks. We assemble a comprehensive view of recent population history (≤100 generations), the timespan during which most rare disease-causing alleles arose, by comparing pairwise haplotype sharin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 836c81ee-6962-50a0-a437-d0f6b151fc3a
DOI: 10.1101/200113

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Haplotype sharing provides insights into fine-scale population history and disease in FinlandDOI 10.1101/200113Read

Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland.Semantic proximity Read

Patterns of genetic connectedness between modern and medieval Estonian genomes reveal the origins of a major ancestry component of the Finnish population.Semantic proximity Read

The genome-wide patterns of variation expose significant substructure in a founder population.Semantic proximity Read

The Finnish genetic heritage in 2022 - from diagnosis to translational research.Semantic proximity Read

FinnGen provides genetic insights from a well-phenotyped isolated population.Semantic proximity Read

FinnGen: Unique genetic insights from combining isolated population and national health register dataSemantic proximity Read

An efficient method to identify, date, and describe admixture events using haplotype information.Semantic proximity Read

A genome-wide analysis of population structure in the Finnish Saami with implications for genetic association studies.Semantic proximity Read

Revealing the recent demographic history of Europe via haplotype sharing in the UK Biobank.Semantic proximity Read

Fine-scale population structure and the era of next-generation sequencing.Semantic proximity Read

Exome sequencing identifies high-impact trait-associated alleles enriched in FinnsSemantic proximity Read

Demographic history and rare allele sharing among human populations.Semantic proximity Read