Article
From Design to in Vivo Active Organometallic-Containing Antimycotic Agents
2020-07-20
Abstract excerpt
Fungal infections are an alarming global problem, most importantly for immunocompromised patients in a hospital environment. The appearance of multidrug resistance in several fungal species is a strong indication that alternative treatments are required. Azoles represent the mainstay of antifungal drugs, and their mode of action involves the binding mode of these molecules to the fungal lanosterol 14α-demethy...
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Identifiers and source
- Literature Corpus work
- 8316a622-5a82-5fec-be24-deb95ca361a7
- DOI
- 10.26434/chemrxiv.12672794.v1
