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Integrated Multi-Omics and Transcriptomic Validation Analysis of TP53, ATM, BRCA1, EGFR, and KRAS Reveals Prognostic Significance in Lung Cancer

2026-05-13

Abstract excerpt

<title>Abstract</title> <p>Lung cancer remains one of the leading causes of cancer-related mortality worldwide, necessitating improved understanding of its molecular mechanisms for effective diagnosis and therapy. In the present study, an integrated multi-omics bioinformatics approach combined with independent transcriptomic validation was employed to investigate the prognostic significance of five key genes—TP53...

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Literature Corpus work
82f32ba2-f59d-56c1-85d3-ff7f6a35acd8
DOI
10.21203/rs.3.rs-9683939/v1
Open publication

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Integrated Multi-Omics and Transcriptomic Validation Analysis of TP53, ATM, BRCA1, EGFR, and KRAS Reveals Prognostic Significance in Lung CancerDOI 10.21203/rs.3.rs-9683939/v1
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