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Article

Multi-omics characterization and machine learning of lung adenocarcinoma molecular subtypes to guide precise chemotherapy and immunotherapy.

Frontiers in immunology - 1 Jan 2024

Zhang Yi, Wang Yuzhi, Qian Haitao

Abstract excerpt

Background: Lung adenocarcinoma (LUAD) is a heterogeneous tumor characterized by diverse genetic and molecular alterations. Developing a multi-omics-based classification system for LUAD is urgently needed to advance biological understanding. Methods: Data on clinical and pathological characteristics, genetic alterations, DNA methylation patterns, and the expression of mRNA, lncRNA, and microRNA, along with...

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Identifiers

PMID: 39669580
DOI: 10.3389/fimmu.2024.1497300
PMCID: PMC11634853

Genes

SLC2A1
CCK

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