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Article

Comprehensive multi-omics integration uncovers mitochondrial gene signatures for prognosis and personalized therapy in lung adenocarcinoma.

Journal of translational medicine - 21 Oct 2024

Zhang Wenjia, Zhao Lei, Zheng Tiansheng, Fan Lihong, Wang Kai, Li Guoshu

Abstract excerpt

The therapeutic efficacy of lung adenocarcinoma (LUAD), the most prevalent histological subtype of primary lung cancer, remains inadequate, with accurate prognostic assessment posing significant challenges. This study sought to elucidate the prognostic significance of mitochondrial-related genes in LUAD through an integrative multi-omics approach, aimed at developing personalized therapeutic strategies. Utilizing...

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Identifiers

PMID: 39434164
DOI: 10.1186/s12967-024-05754-y
PMCID: PMC11492473

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