Article

Neoantigens elicit T cell responses in breast cancer

2021-01-13

Abstract excerpt

Neoantigens are tumor-specific antigens that arise from non-synonymous mutations in tumor cells. However, their effect on the immune responses in tumor microenvironment are still unclear in breast cancer.We performed whole exome and RNA sequencing of 31 fresh breast cancer tissues and neoantigen prediction on the non-synonymous single nucleotide variants (nsSNVs) among exonic mutations. Neoantigen profiles were de...

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Literature Corpus work: ac9621da-9670-598d-b3ca-6d572687a377
DOI: 10.21203/rs.3.rs-127577/v1

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