Article

Cancer immunoediting by melanocyte differentiation antigen-specific T cells determines response to immune checkpoint inhibition

2021-05-03

Abstract excerpt

<title>Abstract</title> <p>T cells are critical in cancer immune surveillance but they can also shape tumor immunogenicity, described as cancer immunoediting. Melanoma patients commonly harbor T cells recognizing melanocyte differentiation antigens (MDAs). However, the roles of MDA-specific T cells in shaping melanoma immunogenicity and the response to immune checkpoint inhibition remain elusive. Here, we prospec...

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Literature Corpus work: 82cd42df-2a86-5529-83db-8e0eeefc67ec
DOI: 10.21203/rs.3.rs-403313/v1

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