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Article

The role of microRNAs on doxorubicin drug resistance in breast cancer

4 May 2021

Abstract excerpt

OBJECTIVES: Resistance to chemotherapeutic drugs is a serious challenge for effective therapy of cancers. Doxorubicin is a drug which is typically used for breast cancer treatment. Several mechanisms are involved in resistance to doxorubicin including overexpression of ATP-binding cassette (ABC) transporters, altering apoptosis, autophagy and cell cycle arrest. In this review, we focus on the potential effects of...

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PMID: 33942851
DOI: 10.1093/jpp/rgaa031

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