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Mechanisms of Cancer Drug Resistance

1 Feb 2002

Abstract excerpt

The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer treatment that is 100% effective against disseminated cancer. Resistance to treatment with anticancer drugs results from a variety of factors including individual variations in patients and somatic cell genetic differences in tumors, even those from the same tissue of origin. Frequently resistance is intrinsic to the...

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PMID: 11818492
DOI: 10.1146/annurev.med.53.082901.103929

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