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Article

Nckx30c, a Drosophila K+-dependent Na+/Ca2+ exchanger, regulates temperature-sensitive convulsions and age-related neurodegeneration.

Journal of neurogenetics - 1 Jan 2026

Majlish Al Nahian Khan, Bourgeois Sophia, Lye Shu Hui, Landaverde Saul, Cytron Emilia, Cline Megan, Bolus Harris, Correll Robert N, Iyengar Atulya, Chtarbanova Stanislava

Abstract excerpt

Calcium (Ca2+) homeostasis is fundamental to neuronal physiology, including in the regulation of membrane excitability and synaptic transmission. Disruptions in the ion transporters regulating Ca2+ influx and efflux are clearly linked to seizure disorders and age-related neurodegenerative disease. Yet, the specific contributions of variants in genes encoding these transporters to neurological disease remain to be...

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Identifiers

PMID: 42002773
DOI: 10.1080/01677063.2026.2655158

Genes

SLC24A2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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