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Analysis of rare coding variants in 470,000 exome-sequenced subjects characterises contributions to risk of type 2 diabetes

2023-10-23

Abstract excerpt

<h4>Aims</h4> To follow up results from an earlier study using an extended sample of 470,000 exome-sequenced subjects to identify genes associated with type 2 diabetes (T2D) and to characterise the distribution of rare variants in these genes. <h4>Materials and methods</h4> Exome sequence data for 470,000 UK Biobank participants was analysed using a combined phenotype for T2D obtained from diagnostic and prescript...

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Literature Corpus work
81c7e7e9-2bc3-5c53-931f-eb0b6d487ed3
DOI
10.1101/2023.10.23.23297410
Open publication

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Analysis of rare coding variants in 470,000 exome-sequenced subjects characterises contributions to risk of type 2 diabetesDOI 10.1101/2023.10.23.23297410
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