Article
Insights on the emergence of Mycobacterium tuberculosis from the analysis of Mycobacterium kansasii.
Genome biology and evolution - 25 Feb 2015
Wang Joyce, McIntosh Fiona, Radomski Nicolas, Dewar Ken, Simeone Roxane, Enninga Jost, Brosch Roland, Rocha Eduardo P, Veyrier Frédéric J, Behr Marcel A
Abstract excerpt
By phylogenetic analysis, Mycobacterium kansasii is closely related to Mycobacterium tuberculosis. Yet, although both organisms cause pulmonary disease, M. tuberculosis is a global health menace, whereas M. kansasii is an opportunistic pathogen. To illuminate the differences between these organisms, we have sequenced the genome of M. kansasii ATCC 12478 and its plasmid (pMK12478) and conducted side-by-side in...
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