Article

A bidirectional <i>nanAKE</i> locus enables sialic acid catabolism in gut microbiome member <i>Hungatella hathewayi</i>

2026-05-18

Abstract excerpt

Sialic acids are abundant components of host- and diet-derived glycans in the human gut and serve as important nutrients that shape microbial fitness and interspecies competition. Excess free sialic acids are also linked to inflammation and pathogen susceptibility. While well-studied gut bacteria such as E. coli and Bacteroides spp. catabolize sialic acids via the NanAKE or NanLE-RokA pathways, the metabolic cap...

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Literature Corpus work: 256e5d2b-7442-52fc-8eb1-507e3472c8cf
DOI: 10.64898/2026.05.18.725967

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